After completing his formal education, Andrew Witty applied for jobs at Unilever and Austin Rover but wanted more options.
His flatmate later told him about Glaxo UK, and he started working as a management trainee in Glaxo UK in 1985.
He later became a Sales Representative for the Respiratory business, and later worked in various positions in the Marketing department. He later became the Director of Pharmacy and Distribution.
In 1993, he became the Managing Director of Glaxo South Africa and later Area Director for GlaxoWellcome, South and East Africa.
He later became the Vice President and General Manager of Marketing for the US arm of GlaxoWellcome Inc., the group’s US subsidiary and settled in North Carolina.
He was later appointed as the Senior Vice President, of Asia Pacific and settled in Singapore in 1999.
From 2000 to 2002, he served as an economic adviser to the governor of Guangzhou, China.
In 2003, he became the President of GSK Europe and became a member of the Corporate Executive Team.
In 2008, he became the CEO of GlaxoSmithKline plc and earned an annual salary of £948,000 and other compensation around £2,180,000.

Andrew Witty in 2008
From 2010 until 2015, he served on the business advisory board of then-Prime Minister of the United Kingdom, David Cameron.
He served as the chancellor of the University of Nottingham from 1 January 2013 to November 2017.

Andrew Witty after becoming the Chancellor of the University of Nottingham
From 2013 to 2015, Witty was a member of the UNAIDS–Lancet Commission for Defeating AIDS and Advancing Global Health.
In 2017, he resigned from the position of CEO of GSK.
From 2017 until 2018, Witty became the head of the National Health Service’s Accelerated Access Collaborative.
In 2017, the University of Nottingham announced the Witty Entrepreneurial Scholarship.
In July 2018, Witty became CEO of Optum, a division of UnitedHealth Group and became the president of UnitedHealth in November 2019, holding dual roles at once.
He later helped the World Health Organization to develop a COVID-19 vaccine.
In February 2021, he became the CEO of UnitedHealth Group.
In May 2024, he accepted before the U.S. Senate Committee on Finance that they paid a $22 million ransom to the hackers who hacked into its subsidiary Change Healthcare.
In November 2024, the Sir Andrew Witty Scholarship for Leaders in Healthcare at Imperial College Business School was announced.
He made headlines in December 2024 after Brian Thompson’s
murder.
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